BDBM756211 US12350272, Compound 241

SMILES CN1CCC(Nc2nc(Nc3ccc(Oc4ccc(F)c(F)c4)cc3)c3c(=O)[nH]cc(Br)c3n2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 756211   

TargetTyrosine-protein kinase receptor UFO(Human)
Oscotec

US Patent
LigandPNGBDBM756211(US12350272, Compound 241)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula (I) as obtained above were initially diluted to 10 nM in 100% DMSO (CALBIOCHEM™) for storage and made into kinase buffer solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Oscotec

US Patent
LigandPNGBDBM756211(US12350272, Compound 241)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula (I) as obtained above were initially diluted to 10 nM in 100% DMSO (CALBIOCHEM™) for storage and made into kinase buffer solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Oscotec

US Patent
LigandPNGBDBM756211(US12350272, Compound 241)
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds of Formula (I) as obtained above were initially diluted to 10 nM in 100% DMSO (CALBIOCHEM™) for storage and made into kinase buffer solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent