BDBM756223 US2010/054853, Compound 8::(5 -2-(pyrrolidin-3 -ylamino)-4-(4-trifluoromethylamino)pyrido [4,3 -djpyrimidin- 5(6H)-one::WO2011053861, Compound 8

SMILES O=c1[nH]ccc2nc(N[C@H]3CCNC3)nc(Nc3ccc(C(F)(F)F)cc3)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756223   

TargetTyrosine-protein kinase JAK2(Human)
Oscotec

US Patent
LigandPNGBDBM756223(US2010/054853, Compound 8 | (5 -2-(pyrrolidin-3 -y...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula (I) as obtained above were initially diluted to 10 nM in 100% DMSO (CALBIOCHEM™) for storage and made into kinase buffer solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Oscotec

US Patent
LigandPNGBDBM756223(US2010/054853, Compound 8 | (5 -2-(pyrrolidin-3 -y...)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula (I) as obtained above were initially diluted to 10 nM in 100% DMSO (CALBIOCHEM™) for storage and made into kinase buffer solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent