BDBM756224 WO2011053861, Compound 136

SMILES O=c1[nH]ccc2nc(N[C@H]3CCNC3)nc(Nc3ccc(N4CCOCC4)cc3)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756224   

TargetTyrosine-protein kinase JAK2(Human)
Oscotec

US Patent
LigandPNGBDBM756224(WO2011053861, Compound 136)
Affinity DataIC50: 5.5nMAssay Description:Compounds of Formula (I) as obtained above were initially diluted to 10 nM in 100% DMSO (CALBIOCHEM™) for storage and made into kinase buffer solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Oscotec

US Patent
LigandPNGBDBM756224(WO2011053861, Compound 136)
Affinity DataIC50: 55nMAssay Description:Compounds of Formula (I) as obtained above were initially diluted to 10 nM in 100% DMSO (CALBIOCHEM™) for storage and made into kinase buffer solutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent