BDBM756252 (E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- quinoxalin-2-yl)-5-methyl- 1H-pyrazol-1-yl)piperi- dine-1-carbonyl)-3- fluoroazetidin-1-yl)-4- (dimethylamino)but-2- en-1-one::US12351571, Example 17

SMILES COc1cc(Nc2ccc3ncc(-c4cnn(C5CCN(C(=O)C6(F)CN(C(=O)/C=C/CN(C)C)C6)CC5)c4C)nc3c2)cc(OC)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 756252   

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM756252((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 5nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM756252((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 48nMAssay Description:Table EB: FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM756252((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 102nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM756252((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 118nMAssay Description:Table EB: FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM756252((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 376nMAssay Description:Table EB: FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent