BDBM756255 (R,E)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)- quinoxalin-2-yl)-1H- pyrazol-1-yl)pyrrolidine- 1-carbonyl)azetidin-1-yl)- 4-(dimethylamino)but-2- en-1-one::US12351571, Example 20

SMILES COc1cc(Nc2ccc3ncc(-c4cnn([C@@H]5CCN(C(=O)C6CN(C(=O)/C=C/CN(C)C)C6)C5)c4)nc3c2)cc(OC)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 756255   

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM756255((R,E)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)-...)
Affinity DataIC50: 5nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM756255((R,E)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)-...)
Affinity DataIC50: 42nMAssay Description:Table EB: FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM756255((R,E)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)-...)
Affinity DataIC50: 53nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM756255((R,E)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)-...)
Affinity DataIC50: 107nMAssay Description:Table EB: FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM756255((R,E)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)-...)
Affinity DataIC50: 194nMAssay Description:Table EB: FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent