BDBM756256 (R)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)- quinoxalin-2-yl)-1H- pyrazol-1-yl)pyrrolidine- 1-carbonyl)azetidin-1- yl)prop-2-en-1-one::US12351571, Example 21

SMILES C=CC(=O)N1CC(C(=O)N2CC[C@@H](n3cc(-c4cnc5ccc(Nc6cc(OC)cc(OC)c6)cc5n4)cn3)C2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 756256   

LigandPNGBDBM756256((R)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 5nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756256((R)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 37nMAssay Description:Table EB: FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756256((R)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 38nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756256((R)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 187nMAssay Description:Table EB: FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756256((R)-1-(3-(3-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 295nMAssay Description:Table EB: FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent