BDBM756257 (E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- quinoxalin-2-yl)-3- methyl-1H-pyrazol-1-yl)- piperidine-1-carbonyl)-3- fluoroazetidin-1-yl)-4- (dimethylamino)but-2-en- 1-one::US12351571, Example 22

SMILES COc1cc(Nc2ccc3ncc(-c4cn(C5CCN(C(=O)C6(F)CN(C(=O)/C=C/CN(C)C)C6)CC5)nc4C)nc3c2)cc(OC)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 756257   

LigandPNGBDBM756257((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 4nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756257((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 19nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756257((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 79nMAssay Description:Table EB: FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756257((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 84nMAssay Description:Table EB: FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756257((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 131nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756257((E)-1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- q...)
Affinity DataIC50: 339nMAssay Description:Table EB: FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent