BDBM756259 1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- quinoxalin-2-yl)-1H- pyrazol-1-yl)piperidine- 1-carbonyl)-3-methoxy- azetidin-1-yl)prop-2-en- 1-one::US12351571, Example 24

SMILES C=CC(=O)N1CC(OC)(C(=O)N2CCC(n3cc(-c4cnc5ccc(Nc6cc(OC)cc(OC)c6)cc5n4)cn3)CC2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 756259   

LigandPNGBDBM756259(1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- quino...)
Affinity DataIC50: 8nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756259(1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- quino...)
Affinity DataIC50: 9nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756259(1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- quino...)
Affinity DataIC50: 24nMAssay Description:Table EB: FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756259(1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- quino...)
Affinity DataIC50: 53nMAssay Description:Table EA: The potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756259(1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- quino...)
Affinity DataIC50: 211nMAssay Description:Table EB: FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756259(1-(3-(4-(4-(7-((3,5- dimethoxyphenyl)amino)- quino...)
Affinity DataIC50: 229nMAssay Description:Table EB: FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent