BDBM756295 3-(2,6-difluoro-3,5- dimethoxyphenyl)-1- ethyl-7-(1-(2- morpholinoethyl)-1H- pyrazol-4-yl)-1,6- naphthyridin-2(1H)- one::US12351576, Example 29

SMILES CCn1c(=O)c(-c2c(F)c(OC)cc(OC)c2F)cc2cnc(-c3cnn(CCN4CCOCC4)c3)cc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756295   

TargetFibroblast growth factor receptor 2(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756295(3-(2,6-difluoro-3,5- dimethoxyphenyl)-1- ethyl-7-(...)
Affinity DataIC50: 5nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756295(3-(2,6-difluoro-3,5- dimethoxyphenyl)-1- ethyl-7-(...)
Affinity DataIC50: 7.5nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent