BDBM756297 1-(cyclopropylmethyl) 3-(2,6-dichloro-3,5- dimethoxyphenyl)-7- (1-methyl-1H-pyrazol- 4-yl)-1,6-naphthyridin- 2(1H)-one::US12351576, Example 4

SMILES COc1cc(OC)c(Cl)c(-c2cc3cnc(-c4cnn(C)c4)cc3n(CC3CC3)c2=O)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756297   

TargetFibroblast growth factor receptor 2(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756297(1-(cyclopropylmethyl) 3-(2,6-dichloro-3,5- dimetho...)
Affinity DataIC50: 5nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756297(1-(cyclopropylmethyl) 3-(2,6-dichloro-3,5- dimetho...)
Affinity DataIC50: 30nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent