BDBM756310 3-(2,6-dichloro-3,5- dimethoxyphenyl)-1- ethyl-7-(1-(1- (methylsulfonyl)azetidin- 3-yl)-1H-pyrazol-4- yl)-1,6-naphthyridin- 2(1H)-one::US12351576, Example 11

SMILES CCn5c(=O)c(c1c(Cl)c(OC)cc(OC)c1Cl)cc4cnc(c3cnn(C2CN(S(C)(=O)=O)C2)c3)cc45

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756310   

TargetFibroblast growth factor receptor 2(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756310(3-(2,6-dichloro-3,5- dimethoxyphenyl)-1- ethyl-7-(...)
Affinity DataIC50: 5nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756310(3-(2,6-dichloro-3,5- dimethoxyphenyl)-1- ethyl-7-(...)
Affinity DataIC50: 30nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent