BDBM756315 2-(5-(3-(2,6-difluoro- 3,5- dimethoxyphenyl)-2- oxo-1- (tetrahydrofuran-3- yl)-1,2-dihydro-1,6- naphthyridin-7- yl)pyridin-2-yl)-2- methylpropanenitrile::US12351576, Example 40

SMILES N#CC(C)(C)c1ccc(-c2cc3c(cn2)cc(-c2c(F)c(OC)cc(OC)c2F)c(=O)n3C2CCOC2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756315   

TargetFibroblast growth factor receptor 2(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756315(2-(5-(3-(2,6-difluoro- 3,5- dimethoxyphenyl)-2- ox...)
Affinity DataIC50: 5nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756315(2-(5-(3-(2,6-difluoro- 3,5- dimethoxyphenyl)-2- ox...)
Affinity DataIC50: 7.5nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent