BDBM756319 1-(5-(3-(2,6-dichloro- 3,5-dimethoxyphenyl)- 2-oxo-1- (tetrahydrofuran-3-yl)- 1,2-dihydro-1,6- naphthyridin-7- yl)pyridin-2- yl)cyclobutane-1- carbonitrile::US12351576, Example 16

SMILES COc1cc(OC)c(Cl)c(-c2cc3cnc(-c4ccc(C5(C#N)CCC5)nc4)cc3n(C3CCOC3)c2=O)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756319   

TargetFibroblast growth factor receptor 2(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756319(1-(5-(3-(2,6-dichloro- 3,5-dimethoxyphenyl)- 2-oxo...)
Affinity DataIC50: 30nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM756319(1-(5-(3-(2,6-dichloro- 3,5-dimethoxyphenyl)- 2-oxo...)
Affinity DataIC50: 275nMAssay Description:1. The kinase reaction in the present invention was carried out in 384-well plates, the kinase(Carna) at a certain concentration and ATP at a certain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent