BDBM756566 US20250215013, Example 5

SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4c(c3)[nH]c(=O)c3sccc34)CC2)c(C)n1

InChI Key InChIKey=QNPIRVLIJKKNNX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756566   

TargetPoly [ADP-ribose] polymerase 1(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 756566BDBM756566(US20250215013, Example 5)
Affinity DataIC50: 0.770nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetProtein cereblon/PARP2(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 756566BDBM756566(US20250215013, Example 5)
Affinity DataIC50: 10.1nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent