BDBM756725 US20250215014, Compound 67::US20250223301, Compound 67

SMILES CCC(c1ccc(C(F)(F)F)cc1)N1C[C@H]2COc3c(c4nc(C#N)ccc4n(C)c3=O)N2C[C@H]1CC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 756725   

TargetDiacylglycerol kinase alpha(Human)
Inventisbio

US Patent
LigandPNGBDBM756725(US20250215014, Compound 67 | US20250223301, Compou...)
Affinity DataIC50: 4nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Inventisbio

US Patent
LigandPNGBDBM756725(US20250215014, Compound 67 | US20250223301, Compou...)
Affinity DataIC50: 10nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Inventisbio

US Patent
LigandPNGBDBM756725(US20250215014, Compound 67 | US20250223301, Compou...)
Affinity DataIC50: 10nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Inventisbio

US Patent
LigandPNGBDBM756725(US20250215014, Compound 67 | US20250223301, Compou...)
Affinity DataIC50: 16nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent