BDBM756765 US20250215014, Compound 108::US20250223301, Compound 108

SMILES CC[C@@H]1CN2c3c(c(=O)n(C)c4ccc(C#N)nc34)OC[C@H]2CN1[C@H](CC)c1ccc(C(F)(F)F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 756765   

LigandPNGBDBM756765(US20250215014, Compound 108 | US20250223301, Compo...)
Affinity DataIC50: 10nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756765(US20250215014, Compound 108 | US20250223301, Compo...)
Affinity DataIC50: 26nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756765(US20250215014, Compound 108 | US20250223301, Compo...)
Affinity DataIC50: 55nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM756765(US20250215014, Compound 108 | US20250223301, Compo...)
Affinity DataIC50: 242nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent