BDBM757025 N-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidin-4-yl)-5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)picolinamide ::US20250222116, Compound 10

SMILES CCc1cc2ncc(CN3CCN(c4ccc(C(=O)NC5CCN(c6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)nc4)CC3)cc2[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 757025   

TargetPoly [ADP-ribose] polymerase 1(Human)
Xizang Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM757025(N-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindo...)
Affinity DataIC50: 0.320nMAssay Description:PARP1, PARP2 and PARP7 chemical fluorescence detection kits were all purchased from BPS Bioscience. The histone solution in the kit was diluted 5× wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetProtein cereblon/PARP2(Human)
Xizang Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM757025(N-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindo...)
Affinity DataIC50: 41nMAssay Description:PARP1, PARP2 and PARP7 chemical fluorescence detection kits were all purchased from BPS Bioscience. The histone solution in the kit was diluted 5× wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Xizang Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM757025(N-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindo...)
Affinity DataIC50: 91nMAssay Description:PARP1, PARP2 and PARP7 chemical fluorescence detection kits were all purchased from BPS Bioscience. The histone solution in the kit was diluted 5× wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent