BDBM757042 5-((1S,6R)-5-((3-ethyl-2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-7-yl)methyl)-2,5-diazabicyclo[4.2.0]octan-2-yl)-N-methylpicolinamide and 5-((1R,6S)-5-((3-ethyl-2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-7-yl)methyl)-2,5-diazabicyclo[4.2.0]octan-2-yl)-N-methylpicolinamide::US20250221987, Example 11-1

SMILES CCc1nc2ncc(CN3CCN(c4ccc(C(=O)NC)nc4)[C@H]4CC[C@H]43)cc2[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757042   

TargetPoly [ADP-ribose] polymerase 1(Human)
Acerand Therapeutics (Hong Kong)

US Patent
LigandPNGBDBM757042(5-((1S,6R)-5-((3-ethyl-2-oxo-1,2-dihydropyrido[2,3...)
Affinity DataIC50: 3.90nMAssay Description:1) 50 ng/mL of histone coating buffer was prepared with 1×PBS, and 25 μL of coating buffer was transferred to a 384-well reaction plate, which was co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Acerand Therapeutics (Hong Kong)

US Patent
LigandPNGBDBM757042(5-((1S,6R)-5-((3-ethyl-2-oxo-1,2-dihydropyrido[2,3...)
Affinity DataIC50: 272nMAssay Description:1) 100 ng/mL of histone coating buffer was prepared with 1×PBS, and 25 μL of coating buffer was transferred to a 384-well reaction plate, which was c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent