BDBM757050 N-methyl-5-((1S,6R)-5-((6-oxo-6,8,9,10-tetrahydro-5H-pyrano[2,3-c][1,5]naphthyridin-3-yl)methyl)-2,5-diazabicyclo[4.2.0]octan-2-yl)picolinamide and N-methyl-5-((1R,6S)-5-((6-oxo-6,8,9,10-tetrahydro-5H-pyrano[2,3-c][1,5]naphthyridin-3-yl)methyl)-2,5-diazabicyclo[4.2.0]octan-2-yl)picolinamide::US20250221987, Example 31-1

SMILES CNC(=O)c1ccc(N2CCN(Cc3cnc4c5c(c(=O)[nH]c4c3)OCCC5)[C@H]3CC[C@H]32)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757050   

TargetPoly [ADP-ribose] polymerase 1(Human)
Acerand Therapeutics (Hong Kong)

US Patent
LigandPNGBDBM757050(N-methyl-5-((1S,6R)-5-((6-oxo-6,8,9,10-tetrahydro-...)
Affinity DataIC50: 0.300nMAssay Description:1) 50 ng/mL of histone coating buffer was prepared with 1×PBS, and 25 μL of coating buffer was transferred to a 384-well reaction plate, which was co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Acerand Therapeutics (Hong Kong)

US Patent
LigandPNGBDBM757050(N-methyl-5-((1S,6R)-5-((6-oxo-6,8,9,10-tetrahydro-...)
Affinity DataIC50: 91nMAssay Description:1) 100 ng/mL of histone coating buffer was prepared with 1×PBS, and 25 μL of coating buffer was transferred to a 384-well reaction plate, which was c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent