BDBM757087 Methyl ((S)-1-((1R,2S,5R)-2-(((S)-1-(cyclopropylamino)-6,6-difluoro-1,2-dioxoheptan-3-yl)carbamoyl)-7,7-dimethyl-3-azabicyclo[3.2.0]heptan-3-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate::US20250223259, Example 25

SMILES COC(=O)N[C@H](C(=O)N2C[C@@H]1CC(C)(C)[C@@H]1[C@H]2C(=O)N[C@@H](CCC(C)(F)F)C(=O)C(=O)NC3CC3)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757087   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757087(Methyl ((S)-1-((1R,2S,5R)-2-(((S)-1-(cyclopropylam...)
Affinity DataIC50: 8.70nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent