BDBM757102 Methyl ((S)-1-((1R,2S,5S)-2- (((S)-6,6-difluoro-1- (methylamino)-1,2-dioxoheptan- 3-yl)carbamoyl)tetrahydro-3- azaspiro[bicyclo[3.1.0]hexane- 6,4''-pyran]-3-yl)-3,3-dimethyl-1- oxobutan-2-yl)carbamate::US20250223259, Example 40

SMILES CNC(=O)C(=O)[C@H](CCC(C)(F)F)NC(=O)[C@@H]1[C@@H]2[C@H](CN1C(=O)[C@@H](NC(=O)OC)C(C)(C)C)C23CCOCC3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757102   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757102(Methyl ((S)-1-((1R,2S,5S)-2- (((S)-6,6-difluoro-1-...)
Affinity DataIC50: 12nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent