BDBM757142 methyl ((S)-1- ((3S,4aS,8aS)-3-(((S)-1- (cyclopropylamino)-6,6- difluoro-1,2-dioxoheptan-3- yl)carbamoyl)octahydroisoq uinolin-2(1H)-yl)-3,3- dimethyl-1-oxobutan-2- yl)carbamate::US20250223259, Example 80

SMILES COC(=O)N[C@H](C(=O)N2C[C@H]1CCCC[C@H]1C[C@H]2C(=O)N[C@@H](CCC(C)(F)F)C(=O)C(=O)NC3CC3)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757142   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757142(methyl ((S)-1- ((3S,4aS,8aS)-3-(((S)-1- (cycloprop...)
Affinity DataIC50: 12nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent