BDBM757159 methyl ((S)-1-((2S,4S or 2R,4R)-2-(((S)-6,6-difluoro- 1 -(methylamino)-1,2- dioxoheptan-3- yl)carbamoyl)-4-fluoro-4- methylpiperidin-1-yl)-3,3- dimethyl-1-oxobutan-2- yl)carbamate::US20250223259, Example 97

SMILES CNC(=O)C(=O)[C@H](CCC(C)(F)F)NC(=O)C1CC(C)(F)CCN1C(=O)[C@@H](NC(=O)OC)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757159   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757159(methyl ((S)-1-((2S,4S or 2R,4R)-2-(((S)-6,6-difluo...)
Affinity DataIC50: 19nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent