BDBM75716 (E)-2-cyano-3-[4-(dimethylamino)phenyl]-2-propenoic acid [1-[methyl-(phenylmethyl)amino]-1-oxopropan-2-yl] ester::(E)-2-cyano-3-[4-(dimethylamino)phenyl]acrylic acid [2-[benzyl(methyl)amino]-2-keto-1-methyl-ethyl] ester::MLS001080957::SMR000710903::[1-[benzyl(methyl)amino]-1-oxopropan-2-yl] (E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enoate::[1-[methyl-(phenylmethyl)amino]-1-oxidanylidene-propan-2-yl] (E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enoate::cid_24819659

SMILES O=C(Nc1cn2cncc2c(N2CCC(F)(F)CC2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

InChI Key InChIKey=PLCIYDOVNIAKTJ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75716   

TargetKinesin-like protein KIF18A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 75716BDBM75716(US20250382298, Compound 27)
Affinity DataIC50: 23.1nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent