BDBM757162 methyl-d3 ((S)-1-((2(S or R),4(S or R))-2-(((S)-6,6- difluoro-1-((methyl- d3)amino)-1,2-dioxoheptan- 3-yl)carbamoyl)-4- (trifluoromethyl)piperidin- 1-yl)-3,3-dimethyl-1- oxobutan-2-yl)carbamate::US20250223259, Example 100

SMILES [2H]C([2H])([2H])NC(=O)C(=O)[C@H](CCC(C)(F)F)NC(=O)C1CC(C(F)(F)F)CCN1C(=O)[C@@H](NC(=O)OC([2H])([2H])[2H])C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757162   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757162(methyl-d3 ((S)-1-((2(S or R),4(S or R))-2-(((S)-6,...)
Affinity DataIC50: 14nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent