BDBM757167 methyl ((S)-1-((1S,3aR,6aS or 1R,3aS,6aR or 1S,3aS,6aR or 1R,3aR,6aS)- 1-(((S)-6,6-difluoro-1- (methylamino)-1,2- dioxoheptan-3- yl)carbamoyl)-5,5- difluorohexahydrocyclopent a[c]pyrrol-2(1H)-yl)-3,3- dimethyl-1-oxobutan-2- yl)carbamate::US20250223259, Example 105

SMILES CNC(=O)C(=O)[C@H](CCC(C)(F)F)NC(=O)C2C1CC(F)(F)CC1CN2C(=O)[C@@H](NC(=O)OC)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757167   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757167(methyl ((S)-1-((1S,3aR,6aS or 1R,3aS,6aR or 1S,3aS...)
Affinity DataIC50: 11nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent