BDBM757168 methyl ((S)-1-((1S,2(S or R),5R)-6,6-dichloro-2-(((S)- 1-(cyclopropylamino)-6,6- difluoro-1,2-dioxoheptan-3- yl)carbamoyl)-3- azabicyclo[3.1.0]hexan-3- yl)-3,3-dimethyl-1- oxobutan-2-yl)carbamate::US20250223259, Example 106

SMILES COC(=O)N[C@H](C(=O)N1C[C@H]3[C@@H](C1C(=O)N[C@@H](CCC(C)(F)F)C(=O)C(=O)NC2CC2)C3(Cl)Cl)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757168   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757168(methyl ((S)-1-((1S,2(S or R),5R)-6,6-dichloro-2-((...)
Affinity DataIC50: 8nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent