BDBM757169 methyl ((S)-1-((2(S or R),3(S or R))-2-(((S)-6,6- difluoro-1-(methylamino)- 1,2-dioxoheptan-3- yl)carbamoyl)-3-((1(S or R),2(R or S))-2- methylcyclopropyl)pyrrolidi n-1-yl)-3,3-dimethyl-1- oxobutan-2-yl)carbamate::US20250223259, Example 107

SMILES CNC(=O)C(=O)[C@H](CCC(C)(F)F)NC(=O)C2C(C1CC1C)CCN2C(=O)[C@@H](NC(=O)OC)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757169   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757169(methyl ((S)-1-((2(S or R),3(S or R))-2-(((S)-6,6- ...)
Affinity DataIC50: 14nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent