BDBM757170 methyl ((S)-1-((2(S or R),4(R or S)-2-(((S)-1- (cyclopropylamino)-6,6- difluoro-1,2-dioxoheptan-3- yl)carbamoyl)-4- (difluoromethyl)piperidin-1- yl)-3,3-dimethyl-1- oxobutan-2-yl)carbamate::US20250223259, Example 108

SMILES COC(=O)N[C@H](C(=O)N1CCC(C(F)F)CC1C(=O)N[C@@H](CCC(C)(F)F)C(=O)C(=O)NC2CC2)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757170   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757170(methyl ((S)-1-((2(S or R),4(R or S)-2-(((S)-1- (cy...)
Affinity DataIC50: 22nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent