BDBM757178 methyl ((S or R)-2- ((1S,3aR,6aS)-1-(((S)-6,6- difluoro-1-(methylamino)- 1,2-dioxoheptan-3- yl)carbamoyl)hexahydrocyc lopenta[c]pyrrol-2(1H)-yl)- 1-(3,3-difluorocyclobutyl)- 2-oxoethyl)carbamate::US20250223259, Example 116

SMILES CNC(=O)C(=O)[C@H](CCC(C)(F)F)NC(=O)[C@@H]2[C@H]1CCC[C@H]1CN2C(=O)C(NC(=O)OC)C3CC(F)(F)C3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757178   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757178(methyl ((S or R)-2- ((1S,3aR,6aS)-1-(((S)-6,6- dif...)
Affinity DataIC50: 16nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent