BDBM757182 ethyl ((S)-1-((1S,3aR,6aS)- 1-(((S)-6,6-difluoro-1- (methylamino)-1,2- dioxoheptan-3- yl)carbamoyl)hexahydrocyc lopenta[c]pyrrol-2(1H)-yl)- 3,3-dimethyl-1-oxobutan-2- yl)carbamate::US20250223259, Example 120

SMILES CCOC(=O)N[C@H](C(=O)N1C[C@@H]2CCC[C@@H]2[C@H]1C(=O)N[C@@H](CCC(C)(F)F)C(=O)C(=O)NC)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757182   

TargetReplicase polyprotein 1a(2019-nCoV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM757182(ethyl ((S)-1-((1S,3aR,6aS)- 1-(((S)-6,6-difluoro-1...)
Affinity DataIC50: 21nMAssay Description:The enzymatic activity of SARS2 coronavirus 3CL protease was determined in a FRET (fluorescence resonance energy transfer)-based assay measuring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent