BDBM757237 US20250223284, Example 2-A

SMILES Cn1c(=O)oc2ccc(-c3ccc(C[C@@H](C#N)NC(=O)[C@@H]4CNC[C@@](C)(O)CO4)cc3)cc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757237   

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandPNGBDBM757237(US20250223284, Example 2-A)
Affinity DataIC50: 39.6nMAssay Description:Table 3: Recombinant human DPP1 enzyme (R&D Systems; Minneapolis, MN) was first proteolytically processed into its mature form using recombinant huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandPNGBDBM757237(US20250223284, Example 2-A)
Affinity DataIC50: 51.7nMAssay Description:Table 2: Test articles were applied to active mouse DPP1 enzyme (R&D Systems; Minneapolis, MN) in Assay Buffer (50 mM MES pH 5.5, 50 mM NaCl, 5 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent