BDBM757238 US20250223284, Example 3-A

SMILES CO[C@@]1(C)CNC[C@@H](C(=O)N[C@H](C#N)Cc2ccc(-c3ccc4oc(=O)n(C)c4c3)cc2)OC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757238   

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandPNGBDBM757238(US20250223284, Example 3-A)
Affinity DataIC50: 130nMAssay Description:Table 2: Test articles were applied to active mouse DPP1 enzyme (R&D Systems; Minneapolis, MN) in Assay Buffer (50 mM MES pH 5.5, 50 mM NaCl, 5 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandPNGBDBM757238(US20250223284, Example 3-A)
Affinity DataIC50: 145nMAssay Description:Table 3: Recombinant human DPP1 enzyme (R&D Systems; Minneapolis, MN) was first proteolytically processed into its mature form using recombinant huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent