BDBM757239 US20250223284, Example 3-B

SMILES CO[C@]1(C)CNC[C@@H](C(=O)N[C@H](C#N)Cc2ccc(-c3ccc4oc(=O)n(C)c4c3)cc2)OC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757239   

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandPNGBDBM757239(US20250223284, Example 3-B)
Affinity DataIC50: 206nMAssay Description:Table 3: Recombinant human DPP1 enzyme (R&D Systems; Minneapolis, MN) was first proteolytically processed into its mature form using recombinant huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandPNGBDBM757239(US20250223284, Example 3-B)
Affinity DataIC50: 251nMAssay Description:Table 2: Test articles were applied to active mouse DPP1 enzyme (R&D Systems; Minneapolis, MN) in Assay Buffer (50 mM MES pH 5.5, 50 mM NaCl, 5 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent