BDBM757279 US20250223284, Example Table 3.26::US20260055093, Compound Table3.26

SMILES Cn1c(=O)oc2ccc(-c3ccc(C[C@@H](C#N)NC(=O)[C@@H]4CNC[C@]5(CCO5)CO4)cc3)cc21

InChI Key InChIKey=WOVWZPWUDRXQJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757279   

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757279BDBM757279(US20250223284, Example Table 3.26 | US20260055093,...)
Affinity DataIC50: 729nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757279BDBM757279(US20250223284, Example Table 3.26 | US20260055093,...)
Affinity DataIC50: 729nMAssay Description:Table 3: Recombinant human DPP1 enzyme (R&D Systems; Minneapolis, MN) was first proteolytically processed into its mature form using recombinant huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent