BDBM757412 US20250223301, Compound 112

SMILES CC[C@H]1CN([C@H](CC)c2ccc(C)nc2)[C@H](CC)CN1c1nc2nncn2c2ccc(C#N)nc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757412   

TargetDiacylglycerol kinase alpha(Human)
Inventisbio

US Patent
LigandPNGBDBM757412(US20250223301, Compound 112)
Affinity DataIC50: 11nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Inventisbio

US Patent
LigandPNGBDBM757412(US20250223301, Compound 112)
Affinity DataIC50: 183nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent