BDBM757424 US20250223301, Compound 124

SMILES CC[C@@H]1CN2c3c(c(=O)n(C)c4ccc(C#N)nc34)OC[C@@H]2CN1[C@H](CC)c1ccc(C(F)(F)F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757424   

TargetDiacylglycerol kinase alpha(Human)
Inventisbio

US Patent
LigandPNGBDBM757424(US20250223301, Compound 124)
Affinity DataIC50: 6nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Inventisbio

US Patent
LigandPNGBDBM757424(US20250223301, Compound 124)
Affinity DataIC50: 114nMAssay Description:The DGKa and DGKz kinase assays were performed using Promega ADP-Glo kit (Promega, Cat #V9102). One microliter test compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/27/2025
Entry Details
US Patent