BDBM757425 6-(Dimethylamino)-N-(methanesulfonyl)-1-benzofuran-2-carboxamide::US12357603, Example 63

SMILES CN(C)c1ccc2cc(C(=O)NS(C)(=O)=O)oc2c1

InChI Key InChIKey=KARWLZSLCZYQNZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757425   

LigandChemical structure of BindingDB Monomer ID 757425BDBM757425(6-(Dimethylamino)-N-(methanesulfonyl)-1-benzofuran...)
Affinity DataIC50: 1.65E+4nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 757425BDBM757425(6-(Dimethylamino)-N-(methanesulfonyl)-1-benzofuran...)
Affinity DataIC50: 2.00E+4nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent