BDBM757501 US12357603, Example 139

SMILES COc1ccc(Cl)c(S(=O)(=O)NC(=O)c2cc3ccc(N(C)C)cc3o2)c1

InChI Key InChIKey=ZLINVSFEFLLVKD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757501   

LigandChemical structure of BindingDB Monomer ID 757501BDBM757501(US12357603, Example 139)
Affinity DataIC50: 329nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 757501BDBM757501(US12357603, Example 139)
Affinity DataIC50: 369nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent