BDBM757781 US20250230129, Compound 5A

SMILES CC(C)C[C@@H](NC(=O)[C@H](CC(=O)[C@H](N)Cc1ccccc1)Cc1ccccc1)C(=O)C[C@H](CCCCN)C(=O)N1CCC2(CC1)CNC(=O)c1ncccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 757781   

TargetKappa-type opioid receptor(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM757781(US20250230129, Compound 5A)
Affinity DataKi:  0.340nMAssay Description:Step 1: 50 μL of a vehicle (1% DMSO) was added into a total binding tube (TB), 50 μL of U69593 (with a final concentration of 1.0×10−5 M) was added i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM757781(US20250230129, Compound 5A)
Affinity DataKi: >1.00E+3nMAssay Description:Step 1: 50 μL of a vehicle (1% DMSO) was added into a total binding tube (TB), 50 μL of DADLE (with a final concentration of 1.0×10−5 M) was added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM757781(US20250230129, Compound 5A)
Affinity DataKi: >1.00E+3nMAssay Description:Step 1: 50 μL of a vehicle (1% DMSO) was added into a total binding tube (TB), 50 μL of DAMGO (with a final concentration of 1.0×10−5 M) was added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent