BDBM757790 US20250230129, Compound 2B

SMILES CN=S1(=O)CCN(C(=O)[C@@H](CCCCN)CC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(=O)[C@H](N)Cc2ccccc2)Cc2ccccc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 757790   

TargetKappa-type opioid receptor(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM757790(US20250230129, Compound 2B)
Affinity DataKi:  0.910nMAssay Description:Step 1: 50 μL of a vehicle (1% DMSO) was added into a total binding tube (TB), 50 μL of U69593 (with a final concentration of 1.0×10−5 M) was added i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM757790(US20250230129, Compound 2B)
Affinity DataKi: >1.00E+3nMAssay Description:Step 1: 50 μL of a vehicle (1% DMSO) was added into a total binding tube (TB), 50 μL of DAMGO (with a final concentration of 1.0×10−5 M) was added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandPNGBDBM757790(US20250230129, Compound 2B)
Affinity DataKi: >1.00E+3nMAssay Description:Step 1: 50 μL of a vehicle (1% DMSO) was added into a total binding tube (TB), 50 μL of DADLE (with a final concentration of 1.0×10−5 M) was added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent