BDBM75781 4-(8-methoxy-5H-pyrimid[5,4-b]indol-4-yl)piperazine-1-carboxylic acid ethyl ester::4-(8-methoxy-5H-pyrimido[5,4-b]indol-4-yl)-1-piperazinecarboxylic acid ethyl ester::MLS000078390::SMR000039980::cid_658919::ethyl 4-(8-methoxy-5H-pyrimido[5,4-b]indol-4-yl)piperazine-1-carboxylate

SMILES O=C(Nc1cn2ccnc2c(N2CC3(CCC3)C2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

InChI Key InChIKey=WOJQVRVHNGYOSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75781   

TargetKinesin-like protein KIF18A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 75781BDBM75781(US20250382298, Compound 29)
Affinity DataIC50: 63.4nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent