BDBM757838 1-[3-[4-[7-[4-fluoro-2-(2-methoxyethoxy)phenyl]-4-(1,2,3,4-tetrahydroisoquinolin-6-yl)thieno[3,2-c]pyridin-6-yl]pyrazol-1-yl]azetidin-1-yl]prop-2-en-1-one ::US20250230138, Compound 44
SMILES C=CC(=O)N1CC(n2cc(-c3nc(-c4ccc5c(c4)CCNC5)c4ccsc4c3-c3ccc(F)cc3OCCOC)cn2)C1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 757838
TargetGTPase KRAS/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
TheRas
US Patent
TheRas
US Patent
Affinity DataIC50: 1.50E+4nMAssay Description:SPR binding experiments were collected on a Biacore 8K Instrument (Cytiva). Neutravidin (Pierce) was amine coupled to the carboxymethylated dextran s...More data for this Ligand-Target Pair
