BDBM75792 2-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]carbonylphenyl]-4-methyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione::2-[3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]phenyl]-4-methyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione::2-[3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]phenyl]-4-methyl-3a,4,7,7a-tetrahydroisoindole-1,3-quinone::2-[3-[[4-(2,3-dimethylphenyl)-1-piperazinyl]-oxomethyl]phenyl]-4-methyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione::MLS000520925::SMR000131334::cid_4321479

SMILES O=C(Nc1cc2nccnc2c(N2CCC(F)(F)CC2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

InChI Key InChIKey=KZNYMRJIWJEMEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75792   

TargetKinesin-like protein KIF18A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 75792BDBM75792(US20250382298, Compound 39)
Affinity DataIC50: 32.2nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent