BDBM758 CHEMBL277034::Hydroxyethylene deriv. 9::tert-butyl N-[(2S,3S,5R)-5-benzyl-5-(benzylcarbamoyl)-3-hydroxy-1-phenylpentan-2-yl]carbamate
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1
InChI Key InChIKey=SDOJFPSFHFRQPP-PKTNWEFCSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 758
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 111nMpH: 5.5 T: 30°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 111nMpH: 5.5 T: 30°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Missouri St. Louis
Curated by ChEMBL
University of Missouri St. Louis
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of human immunodeficiency virus type 1 (HIV-1) protease enzyme.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Missouri St. Louis
Curated by ChEMBL
University of Missouri St. Louis
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Missouri St. Louis
Curated by ChEMBL
University of Missouri St. Louis
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Missouri St. Louis
Curated by ChEMBL
University of Missouri St. Louis
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:In vitro inhibition of HIV-1 proteaseChecked by AuthorMore data for this Ligand-Target Pair