BDBM75804 (5Z)-2-(p-anisidino)-5-vanillylidene-2-thiazolin-4-one::(5Z)-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-2-[(4-methoxyphenyl)amino]-1,3-thiazol-4-one::(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(4-methoxyanilino)-1,3-thiazol-4-one::(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-(4-methoxyanilino)-4-thiazolone::5-[1-(4-Hydroxy-3-methoxy-phenyl)-meth-(Z)-ylidene]-2-(4-methoxy-phenylamino)-thiazol-4-one::MLS000590190::SMR000219349::cid_1839201

SMILES O=C(Nc1cn2ccnc2c(N2CCC(F)(F)CC2)n1)c1ccc(S(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

InChI Key InChIKey=NKPNQUGCYMLOHH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75804   

TargetKinesin-like protein KIF18A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 75804BDBM75804(US20250382298, Compound 73)
Affinity DataIC50: 38.4nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent