BDBM758665 (Racemic) 2''-chloro-5''-methoxy-6- methyl-N-(6-(phenylamino)-4,5,6,7- tetrahydrobenzo[d]thiazol-2-yl)-[4,4''- bipyridine]-3-carboxamide::US20250230171, Compound 133

SMILES COc1cnc(Cl)cc1-c1cc(C)ncc1C(=O)Nc1nc2c(s1)CC(Nc1ccccc1)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 758665   

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758665((Racemic) 2'-chloro-5'-methoxy-6- methyl-N-(6-(phe...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent