BDBM758705 4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(N-propylsulfamoyl)-5,6- dihydro-4H-pyrrolo[3,4-d]thiazol-2- yl)nicotinamide::US20250230171, Compound 270

SMILES CCCNS(=O)(=O)N1Cc2nc(NC(=O)c3cnc(C)cc3-c3cc(C#N)ccc3OC)sc2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 758705   

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758705(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(N-prop...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
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Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent