BDBM759109 US12365685, Example T-1

SMILES CN1CC(c2cnn3c(-c4ccc(NC(=O)Nc5cc(C(F)(F)F)ccc5F)cc4)cnc3c2)C=N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 759109   

TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Shenzhen TargetRx

US Patent
LigandPNGBDBM759109(US12365685, Example T-1)
Affinity DataIC50: 75.8nMAssay Description:Reagents and MaterialsRet wt (Carna, Cat. No. 08-159-10 ug), RET (V804M), Active (Signalchem, Cat. No. R02-12GG), HTRF KinEASE-TK kit (Cisbio, Cat. N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shenzhen TargetRx

US Patent
LigandPNGBDBM759109(US12365685, Example T-1)
Affinity DataIC50: 100nMAssay Description:Reagents and MaterialsRet wt (Carna, Cat. No. 08-159-10 ug), RET (V804M), Active (Signalchem, Cat. No. R02-12GG), HTRF KinEASE-TK kit (Cisbio, Cat. N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent