BDBM759124 2-(3-(5-Amino-6-(isothiazol-5-yl)pyrazin-2- yl)-4-methylphenyl)-3,3,3-trifluoropropane- 1,2-diol, trifluoroacetate salt (single enantiomer isolated, believed to be (S)-2-(3- (5-Amino-6-(isothiazol-5-yl)pyrazin-2-yl)-4- methylphenyl)-3,3,3-trifluoropropane-1,2- diol, trifluoroacetate salt)::US12365668, Example 6

SMILES Cc3cc(c2nc(c1cc(C(O)(CO)C(F)(F)F)ccc1C)cnc2N)sn3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 759124   

LigandPNGBDBM759124(2-(3-(5-Amino-6-(isothiazol-5-yl)pyrazin-2- yl)-4-...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

LigandPNGBDBM759124(2-(3-(5-Amino-6-(isothiazol-5-yl)pyrazin-2- yl)-4-...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent